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Examination of the variations between microcrystalline and nano-hydroxyapatite for defense in opposition to dental caries and remineralizing the enamel.
A development I’ve seen in current months is that practical docs and organic dentists are more and more recommending merchandise that include nano-hydroxyapatite to their sufferers.
What’s hydroxyapatite, or “HA” as it’s generally abbreviated?
HA is kind of merely floor bone with solely the moisture extracted.
Nothing else is added or eliminated.
Hydroxyapatite Protects and Remineralizes Tooth
Analysis printed within the scientific literature convincingly demonstrates that hydroxyapatite offers extremely efficient safety in opposition to dental caries. It additionally provides advantages for tooth remineralization. (1, 2)
In reality, the analysis clearly exhibits that hydroxyapatite’s protecting results on the enamel are nearly as good or higher than fluoride.
Thus, for these wishing to keep away from the organic injury of fluoride publicity, hydroxyapatite is a wonderful and secure various.
The query is, what kind?
Is the nano-hydroxyapatite that’s in a rising share of fluoride-free, remineralizing oral care merchandise the best way to go?
Let’s have a look.
Microcrystalline vs Nano
Microcrystalline hydroxyapatite is the type of dehydrated bone that’s floor to as high-quality a particle measurement as might be carried out mechanically.
Nano-hydroxyapatite is one thing else fully…the particle measurement is massively smaller than the microcrystallized kind.
How a lot smaller?
“Nano” is 1000 occasions smaller than “micro”. (3)
In reality, nanoparticles are so small that they’ll simply breach the partitions of cells and even the nuclear membrane inside a single cell itself…the place DNA is positioned.
Advantages and Dangers
Whereas microcrystalline hydroxyapatite is 100% secure to be used in oral care merchandise (right here’s the place I get mine), it’s best to keep away from the nano model.
Analysis to this point means that there are dangers for mutations to DNA. This happens from the breaching of the nanoparticles previous the nuclear membranes of particular person cells.
Please word that I’m not questioning the analysis on nano-hydroxyapatite.
The advantages are fairly compelling and credible in that it’s certainly useful in defending in opposition to cavities in addition to for remineralization functions.
Nevertheless, there may be RISK in utilizing nano-hydroxyapatite as properly. Some various practitioners are glossing over these risks by recommending merchandise containing them.
Briefly, progress within the evaluation of well being dangers from nanoparticles, aka “nano-toxicology”, is being far outstripped by the fast advances in nano-technology itself. (4)
Thus, sensible shoppers could be properly suggested to make use of warning with merchandise containing nano-hydroxyapatite else they will find yourself as guinea pigs for this expertise.
Whereas anticipated advantages from nano-hydroxyapatite could happen, the unwanted effects may very well be far worse than tooth decay!
Among the dangers from nanoparticles are already recognized within the literature. Dr. Al Danenberg DDS warns about these risks which embrace cytotoxicity, injury, and mutations to mobile DNA. (5)
This happens as a result of breaching of the nuclear membrane (not simply the cell membrane as mentioned within the pro-nanoparticle analysis!).
Nano-Hydroxyapatite Is Not Pure
Briefly, the place microcrystalline hydroxyapatite is a pure substance with a particle measurement that the physique acknowledges and may cope with, nano-hydroxyapatite shouldn’t be.
Nano-hydroxyapatite is the artificial type of hydroxyapatite with confirmed advantages however loads of unknown dangers to the integrity of your DNA.
The particle measurement of nano-hydroxyapatite (or any nanoparticle for that matter) is so tiny that it simply breaches the blood-brain barrier in addition to the nuclear member defending the DNA of each cell.
Abstract
In closing, it is very important know that whereas research present nano-hydroxyapatite to be efficacious, it has not been confirmed secure.
Thus, in case you want to take pleasure in the advantages of remineralizing hydroxyapatite in your oral care merchandise, follow firms that solely use the microcrystalline kind.
As of this writing, I solely know of 1 firm that provides all these merchandise.
That is the hydroxyapatite tooth powder that I take advantage of and advocate that comprises the secure particle (non-nano) kind.
Do you favor to make your personal tooth powder?
This bag of microcrystalline hydroxyapatite is ideal for the DIY oral care recipes you make at residence.
Lastly, what to do with practitioners who’re recommending nano-hydroxyapatite merchandise for you or your kids?
If it had been me on this state of affairs, I’d politely say no.
The medical analysis merely doesn’t assist the protection of nanoparticles for human DNA.
(1, 3) Nano or No-No? Hydroxyapatite Particle Measurement Issues…
(2) Scientific sources of Hydroxyapatite for Oral Well being
(4) Nano-technology and Nano-toxicology
(5) Managing Well being by Minding Your Intestine (and Mouth) Microbiome (beginning at 1:11)